HIV - recentes avanços na pesquisa de fármacos

Química Nova

Wilson Cunico¹  Claudia R. B. Gomes¹  Walcimar T. Vellasco Junior¹ 

[1] ,Instituto de Tecnologia em Fármacos Farmanguinhos Rio de Janeiro RJ ,Brasil

关键词: anti-HIV drugs;    AIDS;    new drugs;   

DOI  :  10.1590/S0100-40422008000800035

来源: SciELO

【 摘 要 】

The development of new antiretroviral drugs is a dynamic process that is continuously fueled by identification of new molecular targets and new compounds for know targets. The current available drugs can be classified into five categories: nucleoside analogues reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, protease inhibitors, integrase inhibitors and entry inhibitors (fusion inhibitors and CCR5 antagonist). In addition, the maturation inhibitors may be considered as potential target for chemotherapeutic intervention. This review presents some anti-HIV agents that have already gone through the advance development process for final approval for the treatment of AIDS.

【 授权许可】

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