Validação de metodologia analítica para doseamento de soluções de lapachol por CLAE

Química Nova

Said G. C. Fonseca²  Leila B. L. Da Silva¹  Rebeka F. Castro¹  Davi P. De Santana¹ 

[1] ,Universidade Federal do Ceará Faculdade de Farmácia, Odontologia e Enfermagem Departamento de FarmáciaFortaleza CE

关键词: lapachol;    validation;    HPLC;   

DOI  :  10.1590/S0100-40422004000100026

来源: SciELO

【 摘 要 】

Lapachol is a naphthoquinone found in several species of the Bignoniaceae family possessing mainly anticancer activity. The present work consists of the development and validation of analytical methodology for lapachol and its preparations. The results here obtained show that lapachol has a low quantification limit, that the analytical methodology is accurate, reproducible, robust and linear over the concentration range 0.5-100 µg/mL of lapachol.

【 授权许可】

CC BY-NC   
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