Functional magnetic resonance imaging in oncology: state of the art

Radiologia Brasileira

Marcos Duarte Guimaraes¹  Alice Schuch¹  Bruno Hochhegger¹  Jefferson Luiz Gross¹  Rubens Chojniak¹  Edson Marchiori¹ 

关键词: Cancer imaging;    Magnetic resonance imaging;    Oncology;    Neoplasia;    Functional imaging;    Diffusion;    Imagem em oncologia;    Ressonância magnética;    Oncologia;    Neoplasia;    Imagem funcional;    Difusão;   

DOI  :  10.1590/S0100-39842014000200013

来源: SciELO

【 摘 要 】

In the investigation of tumors with conventional magnetic resonance imaging, both quantitative characteristics, such as size, edema, necrosis, and presence of metastases, and qualitative characteristics, such as contrast enhancement degree, are taken into consideration. However, changes in cell metabolism and tissue physiology which precede morphological changes cannot be detected by the conventional technique. The development of new magnetic resonance imaging techniques has enabled the functional assessment of the structures in order to obtain information on the different physiological processes of the tumor microenvironment, such as oxygenation levels, cellularity and vascularity. The detailed morphological study in association with the new functional imaging techniques allows for an appropriate approach to cancer patients, including the phases of diagnosis, staging, response evaluation and follow-up, with a positive impact on their quality of life and survival rate.

【 授权许可】

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