Effectiveness Of 2% And 4% Papain Gels In The Healing Of Venous Ulcers

Revista da Escola de Enfermagem da USP

Andréa Pinto Leite Ribeiro¹  Beatriz Guitton Renaud Baptista De Oliveira¹  Marja Ferreira Soares¹  Bruna Maiara Ferreira Barreto¹  Débora Omena Futuro¹  Selma Rodrigues De Castilho¹ 

关键词: Varicose Ulcer;    Leg Ulcer;    Papain;    Treatment Outcome;    Nursing;    Úlcera Varicosa;    Úlcera de la Pierna;    Papaína;    Resultado del Tratamiento;    Enfermería;    Úlcera Varicosa;    Úlcera da Perna;    Papaína;    Resultado do Tratamento;    Enfermagem;   

DOI  :  10.1590/S0080-623420150000300006

来源: SciELO

【 摘 要 】

OBJECTIVE To analyze the effectiveness of 2% and 4% papain gels in tissue repair of venous ulcers. METHOD Quasi-experimental study with consecutive sample of 16 patients with 30 venous ulcers treated at the outpatient clinic of a teaching hospital, from April to November in 2011, using a form for clinical assessment of the patient and its lesion. Variables were analyzed by Wilcoxon and McNemar test (p < 0.05). RESULTS Most participants were female; aged between 51 and 59 years; obese; with hypertension. Regarding ulcers, there was an average decrease of 7.9 cm2 (50% of its original size) in 90 days; 20% of the ulcers completely healed within 56.67 days. There was an increase in epithelialization, significant reduction in the slough and edema, improved depth, in the type and amount of exudate (p < 0.0001). CONCLUSION 2% and 4% papain gels were effective in healing venous ulcers.

【 授权许可】

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