Varicella zoster virus reactivation during or immediately following treatment of tegumentary leishmaniasis with antimony compounds

Memórias do Instituto Oswaldo Cruz

Andrea Barbieri Barros¹  Alex Miranda Rodrigues¹  Mariane Pereira Batista¹  Sidney Munhoz Junior¹  Marcia Hueb¹  Cor Jesus Fontes¹ 

关键词: leishmaniasis;    herpes zoster;    antimony therapy;   

DOI  :  10.1590/0074-0276130563

来源: SciELO

【 摘 要 】

Antimony compounds are the cornerstone treatments for tegumentary leishmaniasis. The reactivation of herpes virus is a side effect described in few reports. We conducted an observational study to describe the incidence of herpes zoster reactivation during treatment with antimony compounds. The global incidence of herpes zoster is approximately 2.5 cases per 1,000 persons per month (or 30 cases per 1,000 persons per year). The estimated incidence of herpes zoster in patients undergoing antimony therapy is higher than previously reported.

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