The efficacy of a chitin synthesis inhibitor against field populations of organophosphate-resistant Aedes aegypti in Brazil

Memórias do Instituto Oswaldo Cruz

Nathalia Giglio Fontoura¹  Diogo Fernandes Bellinato¹  Denise Valle¹  José Bento Pereira Lima¹ 

[1] ,Instituto Oswaldo Cruz-Fiocruz Laboratório de Fisiologia e Controle de Artrópodes Vetores Rio de Janeiro RJ ,Brasil

关键词: Aedes aegypti;    chitin synthesis inhibitors;    temephos;    deltamethrin;    novaluron;    cross-resistance;   

DOI  :  10.1590/S0074-02762012000300014

来源: SciELO

【 摘 要 】

The mosquito Aedes aegypti is the main focus of dengue control campaigns. Because of widespread resistance against conventional chemical insecticides, chitin synthesis inhibitors (CSIs) are considered control alternatives. We evaluated the resistance status of four Brazilian Ae. aegypti populations to both the organophosphate temephos and the pyrethroid deltamethrin, which are used in Brazil to control larvae and adults, respectively. All vector populations exhibited high levels of temephos resistance and varying rates of alterations in their susceptibility to pyrethroids. The effect of the CSI novaluron on these populations was also investigated. Novaluron was effective against all populations under laboratory conditions. Field-simulated assays with partial water replacement were conducted to evaluate novaluron persistence. Bioassays were continued until an adult emergence inhibition of at least 70% was attained. We found a residual effect of eight weeks under indoor conditions and novaluron persisted for five-six weeks in assays conducted in an external area. Our data show that novaluron is effective against the Ae. aegypti populations tested, regardless of their resistance to conventional chemical insecticides.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License