Treating ocular toxoplasmosis: current evidence

Memórias do Instituto Oswaldo Cruz

Mr Stanford²  Re Gilbert¹ 

[1] ,Rayne Institute Dept. Academic Ophthalmology King's College LondonLondon,England

关键词: ocular toxoplasmosis;    treatment;    current evidence;   

DOI  :  10.1590/S0074-02762009000200027

来源: SciELO

【 摘 要 】

The current treatment of ocular toxoplasmosis is controversial. The mainstay of treatment has been pyrimethamine and sulphonamides with or without systemic corticosteroids, but the actual evidence that antibiotics have a beneficial effect in recurrent toxoplasmic retinochoroiditis is unsupported by randomised placebo controlled trials. Thus far there have only been three studies looking at the efficacy of antibiotic treatment, all of which were methodologically weak and two of which were perfomed more than 30 years ago. All studies reported adverse effects from treatment. There is an urgent need for further randomised, double blind, placebo controlled studies for lesions in all parts of the retina and to test the efficacy of adjunctive corticosteroid treatment.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License