Notes on human cases of cystic echinococcosis in Peru

Memórias do Instituto Oswaldo Cruz

Elizabeth Luz Sanchez Romani¹  Rosângela Rodrigues-silva²  Arnaldo Maldonado Jr.²  José Roberto Machado-silva²  Delir Corrêa Gomes² 

[1] ,Instituto Nacional de Salud Centro Nacional de Salud Pública Departamento de ParasitologiaLima,Perú

关键词: Echinococcus granulosus;    cystic echinococcosis;    human cases;    Peru;   

DOI  :  10.1590/S0074-02762006000300020

来源: SciELO

【 摘 要 】

Cystic echinococcosis (CE) is a high prevalent zoonosis in the central and southern Peruvian Andes. Serum samples (n50)frompatients presenting presumptive clinical and radiological diagnosis of CE (group 1), were tested for antibodies against Echinococcus granulosus metacestode using Arc-5 double diffusion assay (DD5), immunoelectrophoresis (IEF), and immunoelectrotransfer blot (EITB) techniques. Serum samples (n18) from patients presenting other parasite infections (paragonomiasis, cysticercosis, and fascioliasis) or healthy blood donors (n15), were designated as control groups. The overall sensitivity of the tests was of 94% (DD5 and IEF tests) or 96% (EITB test). Only patients from group 1 were seropositive for CE. Polypeptides of 21, 31, and 48 kDa were considered positive for CE. Based on these results, this study demonstrates that CE also occurs in other coastal departments (Piura, Ancash, Ica, Arequipa, and Tacna) besides Lima.

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