Distribution and pathogenicity of Trypanosoma cruzi isolated from peridomestic populations of Triatoma infestans and Triatoma guasayana from rural Western Argentina

Memórias do Instituto Oswaldo Cruz

Marta A Lauricella²  Raúl L Stariolo¹  Adelina R Riarte²  Elsa L Segura²  Ricardo E Gürtler¹ 

[1] ,Administración Nacional de Laboratorios e Institutos de Salud ‘Dr. Carlos G. Malbrán’ Instituto Nacional de Parasitología ‘Dr. Mario Fatala Chabén’ Buenos Aires,Argentina

关键词: Trypanosoma cruzi;    Triatoma infestans;    Triatoma guasayana;    Triatoma garciabesi;    Chagas disease;    surveillance;    pathogenicity;    Argentina;   

DOI  :  10.1590/S0074-02762005000200004

来源: SciELO

【 摘 要 】

We assessed the distribution of Trypanosoma cruzi infection in peridomestic triatomines collected manually at a district-wide scale in rural villages around Olta, Western Argentina, and typed the isolated strains according to their pathogenicity to laboratory mice. Of 1623 triatomines examined, only 14 (0.9%) were infected with T. cruzi based on microscopical examination of feces. The prevalence of T. cruzi infection was 0.8% in Triatoma infestans, 2.3% in T. guasayana, and nil in T. garciabesi, T. platensis, and T. eratyrusiformis. Local transmission occurred in kitchens, store-rooms and goat corrals or nearby, though at very low levels. T. cruzi was detected by at least one parasitological method in 11 (79%) of 14 microscope-positive bugs. Hemoculture was the most sensitive method (67%) followed by culture of organ homogenates, histopathology or xenodiagnosis of inoculated suckling mice (55-58%), and culture of microscope-positive bug feces (46%). The evidence suggests that most of the isolated T. cruzi strains would be myotropic type III. Our study establishes for the first time that peridomestic, microscope-positive T. guasayana nymphs were actually infected with T. cruzi, and may be implicated as a putative secondary vector of T. cruzi in domestic or peridomestic sites.

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