Determinants of Human Immunodeficiency Virus (HIV) prevalence in homosexual and bisexual men screened for admission to a cohort study of HIV negatives in Belo Horizonte, Brazil: Project Horizonte

Memórias do Instituto Oswaldo Cruz

Mariângela Carneiro²  Fabíola Adriane Cardoso²  Marília Greco¹  Edson Oliveira¹  Júlio Andrade¹  Dirceu Bartolomeu Greco¹  Carlos Maurício De Figueiredo Antunes¹ 

[1] ,Instituto de Ciências Biológicas Epidemiologia de Doenças Infecciosas e Parasitárias Departamento de Parasitologia

关键词: human immunodeficiency virus prevalence;    risk factors;    homosexual and bisexual men;    open cohort;    Minas Gerais;    Brazil;   

DOI  :  10.1590/S0074-02762003000300006

来源: SciELO

【 摘 要 】

Project Horizonte, an open cohort of homosexual and bisexual human immunodeficiency virus (HIV-1) negative men, is a component of the AIDS Vaccine Program, in Belo Horizonte, Minas Gerais, Brazil. The objective of this study was to compare volunteers testing HIV positive at cohort entry with a sample of those who tested HIV negative in order to identify risk factors for prevalent HIV infection, in a population being screened for enrollment at Project Horizonte. A nested case-control study was conducted. HIV positive volunteers at entry (cases) were matched by age and admission date to three HIV negative controls each. Selected variables used for the current analysis included demographic factors, sexual behavior and other risk factors for HIV infection. During the study period (1994-2001), among the 621 volunteers screened, 61 tested positive for HIV. Cases were matched to 183 HIV negative control subjects. After adjustments, the main risk factors associated with HIV infection were unprotected sex with an occasional partners, OR = 3.7 (CI 95% 1.3-10.6), receptive anal intercourse with an occasional partner, OR = 2.8 (95% CI 0.9-8.9) and belonging to the negro racial group, OR = 3.4 (CI 95% 1.1-11.9). These variables were associated with an increase in the risk of HIV infection among men who have sex with men at the screening for admission to an open HIV negative cohort.

【 授权许可】

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