Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil

Memórias do Instituto Oswaldo Cruz

Mario León Silva-vergara¹  José Carlos Costa Júnior¹  Cristina Hueb Barata¹  Vítor Guilherme Maluf Curi¹  Carlos Giovanni Tiveron Júnior¹  Alan César Teixeira¹ 

[1] ,Faculdade de Medicina do Triângulo Mineiro Departamento de Clínica Médica Disciplina de Doenças Infecciosas e ParasitáriasUberaba MG ,Brasil

关键词: hantavirus;    hantavirus pulmonary syndrome/HPS;    Sin Nombre virus;    Minas Gerais;    Brazil;   

DOI  :  10.1590/S0074-02762002000600005

来源: SciELO

【 摘 要 】

This report describes the epidemiological and clinical-evolutive characteristics of eight patients with hantavirus pulmonary syndrome (HPS) in Uberaba, Minas Gerais, Brazil. A positive history of contact with rodents was present in 100% of the cases. The time between the onset of symptoms and hospital care was, on average, 3.6 days. All patients showed clinical and laboratory findings suggestive of HPS. Elevated urea and creatinine levels were observed in 6 (75%) cases, PO2 was < 60 mmHg in 100% of the cases, and a chest X-ray demonstrated a bilateral interstitial-alveolar infiltrate. The diagnosis was confirmed by the detection of IgM antibodies against Sin Nombre virus by ELISA. Three patients died as a direct consequence of HPS.

【 授权许可】

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