Nuclear rDNA-based molecular clock of the evolution of triatominae (Hemiptera: Reduviidae), vectors of Chagas disease

Memórias do Instituto Oswaldo Cruz

Md Bargues²  A Marcilla²  Jm Ramsey¹  Jp Dujardin¹  Cj Schofield¹  S Mas-coma² 

[1] ,Universidad de Valencia Facultad de Farmacia Departamento de ParasitologíaValencia,España

关键词: Chagas disease;    Triatominae vectors;    nuclear rDNA;    18S gene;    ITS-2 spacer;    molecular clock;    evolution;   

DOI  :  10.1590/S0074-02762000000400020

来源: SciELO

【 摘 要 】

The evolutionary history and times of divergence of triatomine bug lineages are estimated from molecular clocks inferred from nucleotide sequences of the small subunit SSU (18S) and the second internal transcribed spacer (ITS-2) of the nuclear ribosomal DNA of these reduviids. The 18S rDNA molecular clock rate in Triatominae, and Prosorrhynchan Hemiptera in general, appears to be of 1.8% per 100 million years (my). The ITS-2 molecular clock rate in Triatominae is estimated to be around 0.4-1% per 1 my, indicating that ITS-2 evolves 23-55 times faster than 18S rDNA. Inferred chronological data about the evolution of Triatominae fit well with current hypotheses on their evolutionary histories, but suggest reconsideration of the current taxonomy of North American species complexes.

【 授权许可】

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