Characterization of Endotrypanum (Kinetoplastida: Trypanosomatidae), a Unique Parasite Infecting the Neotropical Tree Sloths (Edentata)

Memórias do Instituto Oswaldo Cruz

Antonia M Ramos Franco¹  Gabriel Grimaldi Jr¹ 

[1] ,Instituto Oswaldo CruzRio de Janeiro RJ ,Brasil

关键词: Endotrypanum;    Protozoa;    Kinetoplastida;    Trypanosomatidae;    molecular taxonomy;    enzyme activities;    monoclonal antibodies;    enzyme electrophoresis;    DNA analyses;    mammalian reservoirs;    sandflies vectors;   

DOI  :  10.1590/S0074-02761999000200026

来源: SciELO

【 摘 要 】

This article reviews current concepts of the biology of Endotrypanum spp. Data summarized here on parasite classification and taxonomic divergence found among these haemoflagellates come from our studies of molecular characterization of Endotrypanum stocks (representing an heterogenous population of reference strains and isolates from the Brazilian Amazon region) and from scientific literature. Using numerical zymotaxonomy we have demonstrated genetic diversity among these parasites. The molecular trees obtained revealed that there are, at least, three groups (distinct species?) of Endotrypanum, which are distributed in Central and South America. In concordance with this classification of the parasites there are further newer molecular data obtained using distinct markers. Moreover, comparative studies (based on the molecular genetics of the organisms) have shown the phylogenetic relationships between some Endotrypanum and related kinetoplastid lineages.

【 授权许可】

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