Toxoplasma gondii Antigenuria in Patients with Acquired Immune Deficiency Syndrome

Memórias do Instituto Oswaldo Cruz

Alberto Fachado¹  Lisset Fonseca¹  Luis Fonte¹  Esteban Alberti¹  Raymundo Cox¹  Frank Bandera¹ 

关键词: Toxoplasma gondii antigens;    coagglutination test;    AIDS patients;    neurotoxoplasmosis;   

DOI  :  10.1590/S0074-02761997000500005

来源: SciELO

【 摘 要 】

A longitudinal study was performed with sera and urine of patients with acquired immune deficiency syndrome (AIDS), taken before, during and after clinically Toxoplasma infection. The tested patients were followed for an average of two years. The titres of the specific IgG and IgM antibodies were measured by an indirect fluorescent antibody test (IFAT), and the appearance of circulating antigens of T. gondii was determined in 36 urine samples of 13 patients with neurotoxoplasmosis by means of the coagglutination test. The presence of T. gondii antigens in the urine of AIDS patients by this test was correlated with the immunoblot technique, with clinical symptoms and also with pathological findings. Our results indicate that the detection of T. gondii antigens in the urine of AIDS patients can be regarded as a rapid and efficient method for the diagnosis of acute toxoplasmosis

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License