Development of sporogonic cycle of Plasmodium vivax in experimentally infected Anopheles albimanus mosquitoes

Memórias do Instituto Oswaldo Cruz

Martha L. Salas²  Jackeline F. Romero¹  Yesid Solarte²  Victor Olano¹  Myriam A. Herrera¹  Sócrates Herrera¹ 

[1] ,Fundación Centro de PrimatesCali,Colombia

关键词: malaria;    Plasmodium;    sporozoites;    Anopheles albimanus;   

DOI  :  10.1590/S0074-02761994000600024

来源: SciELO

【 摘 要 】

The sporogonic cycle of Plasmodium vivax was established and maintained under laboratory conditions in two different strains of Anopheles albimanus mosquitoes using as a parasite source blood from human patients or from Aotus monkeys infected with the VCC-2 P.vivax colombian isolate. Both the Tecojate strain isolate from Guatemala and the Cartagena strain from the colombian Pacific coast were susceptible to infections with P.vivax. A higher percentage of Cartagena mosquitoes was infected per trial, however the Tecojate strain developed higher sporozoite loads. Intravenous inoculation of Aotus monkeys with sporozoites obtained from both anopheline strains resulted in successful blood infections. Animals infected with sporozoites from the Tecojate strain presented a patent period of 21-32 days whereas parasitemia appeared between days 19-53 in monkeys infected with sporozites from Cartagena strain.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License