Milky spots reactions to schistosomal mansoni infection

Memórias do Instituto Oswaldo Cruz

H. L. Lenzi¹  D. N. Oliveira²  R. Borojevic¹  J. A. Lenzi² 

[1] ,Instituto Oswaldo Cruz Departamento de Patologia Rio de Janeiro,Brasil

关键词: milky spot;    Schistosoma mansoni;    eosinophil;    peritoneum;   

DOI  :  10.1590/S0074-02761992000900017

来源: SciELO

【 摘 要 】

Milky spots (MS), considered by the authors as a Coelomatic Lympho-myelopoietic Organ (CLMO), present a strong reactivity during experimental schistosomal mansoni infection, characterized by an increase of lymphocytes, macrophages, plasmocytes, mast cells, neutrophils and expression of eosinophil metaplasia. Intraperitoneal injection of purified Schistosoma mansoni (Sm) eggs provoked a rise in the number and size of MS, which developed the sessile marginal and pedunculated types. The authors conclude that egg antigens are, at least partially, responsible for MS reactivity during Sm infection.

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