Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye

Memórias do Instituto Oswaldo Cruz

J. C. B. R. Freitas¹  O. A. F. Presgrave¹  F. F. Fingola¹  M. A. C. Menezes¹  M. C. Vasconcellos²  V. T. Schall²  F. J. R. Paumgartten¹ 

[1] ,Instituto Nacional de Controle de Qualidade em Saúde Departamento de Farmacologia e Toxicologia Rio de Janeiro,Brasil

关键词: Euphorbia splendens;    plants molluscicide;    schistosomiasis;    skin irritation;    eye irritation;    toxicology;   

DOI  :  10.1590/S0074-02761991000600021

来源: SciELO

【 摘 要 】

Aqueous solutions of the molluscicidal latex of Euphorbia splendens are irritant to the rabbit eye in concentrations higher than 0.35% and to the rabbit skin in concentrations higher than 0.5%. Although this irritant potential does not proclude its use as a molluscicide, special precautions are recommended for hanbdling and application of the product and the hazard of skin tumor-promoting potencial should be carefully investigated before its use for schistosomiasis vector control.

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