Natural lectin activity in the haemolymph of Panstrogylus megistus (Heteroptera: Reduvidae)

Memórias do Instituto Oswaldo Cruz

Y. M. Gomes¹  A. F. Furtado¹  A. B. De Carvalho¹ 

[1] ,FIOCRUZ Centro de Pesquisas Aggeu Magalhães Recife,Brasil

关键词: Panstrongylus megistus;    haemolymph;    lectin;    carbohydrate specificity;    Panstrongylus megistus;    hemolinfa;    lectina;    carboidrato-específico;   

DOI  :  10.1590/S0074-02761988000400018

来源: SciELO

【 摘 要 】

The haemolymph of Panstrongylus megistus showed a natural lectin activity for a wide range of vertebrate erythocytes. Agglutination was observed against all vertebrate erythrocytes tested (human ABO, duck, rabbit, mouse, sheep, chicken and cow). Cow erythrocytes showed the lowest titre. Concerning human erythrocytes, the lectin activity was similar in the types A+,B+ and AB+ while the highest activity was observed in the type O+. Determination of minimal inhibitory concentrations was carried out with human erythrocytes type O+. Agglutination was inhibited by several carbohydrates (rhamnose. D-galatose, raffinose, D-lactose and D-fucose). Rhamnose wasreported as the strongest inhibitor (0.78mM). The results suggest the presence of more than one lection in the haemolymph of P. megistus.

【 授权许可】

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