A five year follow-up study of 11 patients with bipolar disorder

Jornal Brasileiro de Psiquiatria

Fernanda Novis²  Elie Cheniaux²  Jesus Landeira-fernandez¹  Marcio Versiani² 

[1] ,Federal University of Rio de Janeiro Institute of Psychiatry

关键词: Bipolar disorder;    disability;    functioning;    prospective studies;    Transtorno bipolar;    incapacidade;    funcionamento;    estudos prospectivos;   

DOI  :  10.1590/S0047-20852010000300008

来源: SciELO

【 摘 要 】

OBJECTIVE: To study the long-term follow-up of patients with bipolar disorder (BPD). METHOD: Eleven outpatients with BPD type I were followed up naturalistically for five years at a university teaching hospital. The Clinical Global Impression Scale (BPD version) was used to evaluate the occurrence of affective episodes, and the Strauss-Carpenter Outcome Scale was used to evaluate social and occupational functioning. RESULTS: The majority of patients were symptomatic most of the time, with predominantly depressive episodes. Overall, patients remained euthymic a mean of 47.7% of the time. Despite a low rate of hospitalization, social and occupational functioning was poor in the majority of patients. A poor disease course with respect to work-related functioning was associated with fewer months of euthymia with a longer duration of depressive episodes. The total number of months of euthymia negatively correlated with the patient's age and disease duration. CONCLUSION: Despite the small sample size, the present findings appear to corroborate previous studies on the evolution of BPD. Most of the patients had a poor disease course, with long symptomatic periods, particularly depressive episodes, and significantly impaired social and occupational functioning.

【 授权许可】

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