Phenotypic and genotypic profile of pyrethroid resistance in populations of the mosquito Aedes aegypti from Goiânia, Central West Brazil

Revista da Sociedade Brasileira de Medicina Tropical

Francesca Guaracyaba Garcia Chapadense¹  Everton Kort Kamp Fernandes¹  José Bento Pereira Lima¹  Ademir Jesus Martins¹  Luana Carrara Silva¹  Welington Tristão Da Rocha¹  Adelair Helena Dos Santos¹  Pedro Cravo¹ 

关键词: Aedes aegypti;    Resistance;    Voltage-gated sodium channel;   

DOI  :  10.1590/0037-8682-0046-2015

来源: SciELO

【 摘 要 】

ABSTRACTINTRODUCTION:The mosquito Aedes aegypti has evolved resistance to pyrethroid insecticides. The present study evaluated Ae. aegypti from Goiânia for the resistant phenotype and for mutations associated with resistance.METHODS:Insecticide dose-response bioassays were conducted on mosquitoes descended from field-collected eggs, and polymerase chain reaction (PCR) was used to genotype 90 individuals at sites implicated in pyrethroid resistance.RESULTS:All mosquito populations displayed high levels of resistance to deltamethrin, as well as high frequencies of the 1016Ile kdr and 1534Cys kdrmutations.CONCLUSIONS:Aedes aegypti populations in the Goiânia area are highly resistant to deltamethrin, presumably due to high frequencies of kdr(knockdown-resistance) mutations.

【 授权许可】

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