Effects of Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers

Revista da Sociedade Brasileira de Medicina Tropical

Lurdete Maria Rocha Gauch¹  Fabíola Silveira-gomes¹  Renata Antunes Esteves¹  Simone Soares Pedrosa¹  Ely Simone Cajueiro Gurgel¹  Alberto Cardoso Arruda¹  Silvia Helena Marques-da-silva¹ 

关键词: Candida albicans;    Germ Tube;    Rosmarinus officinalis;   

DOI  :  10.1590/0037-8682-0137-2013

来源: SciELO

【 摘 要 】

Introduction The aim of this study was to investigate the effects of Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers. Methods Ten C. albicans isolates recovered from denture wearers were tested using 10% fetal bovine serum with or without 4% R. officinalis essential oil. Results The essential oil from R. officinalis completely inhibited germ tube formation in the investigated C. albicans isolates. Conclusions The results demonstrate that the essential oil of R. officinalis modulates C. albicans pathogenicity through its primary virulence factor (i.e., germ tube formation was suppressed).

【 授权许可】

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