Cryptococcus gattii molecular type VGII as agent of meningitis in a healthy child in Rio de Janeiro, Brazil: report of an autochthonous case

Revista da Sociedade Brasileira de Medicina Tropical

Vitor Laerte Pinto Junior²  Marcos Vinicius Da Silva Pone¹  Sheila Moura Pone¹  João Maurício Scarpellini Campos¹  José Roberto Pereira Garrido¹  Ana Cláudia Mamede Wiering De Barros¹  Luciana Trilles¹  Gláucia Gonçalves Barbosa¹  Bernardina Penarrieta Morales¹  Cláudia De Carvalho Falci Bezerra¹  Márcia Dos Santos Lazéra¹ 

[1] ,Oswaldo Cruz FoundationBrasília DF ,Brazil

关键词: Meningoencephalitis;    Immunocompetent;    Cryptococcus gattii;    Meningoencefalite;    Imunocompetente;    Cryptococcus gattii;   

DOI  :  10.1590/S0037-86822010000600032

来源: SciELO

【 摘 要 】

Cryptococcus gattii causes meningoencephalitis in immunocompetent hosts, occurring endemically in some tropical and subtropical regions. Recently, this fungus was involved in an outbreak in Vancouver Island and British Columbia (Canada). In this temperate region, the VGII type is predominant. The paper describes an autochthonous case of meningoencephalitis by C. gattii VGII in a previously health child in Rio de Janeiro, considered nonendemic region of Brazil. The fungus was identified by biochemical tests and the molecular type was determined by URA5-RFLP. The present report highlights the need for clinical vigilance for primary cryptococcal meningitis in nonendemic areas.

【 授权许可】

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