Cryptococcus gattii meningoencephalitis in an HIV-negative patient from the Peruvian Andes

Revista da Sociedade Brasileira de Medicina Tropical

Ericson L. Gutierrez²  Willi Valqui²  Luis Vilchez¹  Lourdes Evangelista¹  Sarita Crispin¹  Mercedes Tello²  Marcos Ñavincopa¹  Vilma Béjar¹  José Gonzáles¹  Alex G. Ortega-loayza¹ 

[1] ,National University of San Marcos Institute of Clinical Research Lima,Peru

关键词: Cryptococcus gatti;    Meningoencephalitis;    Cryptococcus gattii;    Meningoencefalite;   

DOI  :  10.1590/S0037-86822010000400029

来源: SciELO

【 摘 要 】

We report a case of an immunocompetent Peruvian patient from the Andes with a one-month history of meningoencephalitis. Cryptococcus gattii was identified from a cerebrospinal fluid culture through assimilation of D-proline and D-tryptophan as the single nitrogen source. Initially, the patient received intravenous antifungal therapy with amphotericin B. The patient was discharged 29 days after hospitalization and continued with oral fluconazole treatment for ten weeks. During this period, the patient showed clinical improvement with slight right-side residual weakness. Through this case report, we confirm the existence of this microorganism as an infectious agent in Peru.

【 授权许可】

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