Usefulness of serology for the evaluation of Trypanosoma cruzi transmission in endemic areas of Chagas' disease

Revista da Sociedade Brasileira de Medicina Tropical

Roberto Chuit²  Elisabet Subias¹  Analia C. Pérez¹  Irene Paulone¹  Cristina Wisnivesky-colli¹  Elsa L. Segura¹ 

[1] ,Ministério de Salud y Acción Social de la Nation Secretaria de Salud Servido Nacional de ChagasCórdoba,Argentina

关键词: T. cruzi transmission;    Prevention and control;    Field study;    Serodiagnosis;    Transmissão de T. cruzi;    Prevenção e controle;    Estudo de campo;    Sorodiagnóstico;   

DOI  :  10.1590/S0037-86821989000300002

来源: SciELO

【 摘 要 】

Thirteen communities from 7 Argentinian provinces were selected for the evaluation of serology as an indicator of transmission of Chagas disease. Of the communities appraised, 6 did not have a history of previous treatment with insecticides and 7 had received sporadic or continuous insecticide treatment. The inhabitants of 20% of the houses of each locality were studied by serology. The samples were obtained byfinger pricking and 50 fil of blood were mixed with 150μl of 50% glycerine solution in tissue culture media to be assayed by Indirect Hemagglutination and Indirect Immunofluorescence tests. In untreated areas, the prevalence of infection in infants 0-4 years old was 17.5%, reaching to over 22% for the 5-9 year old group, and to 33.3% in 10-14 year old individuals. The prevalence in treated and surveyed areas was 2.6% in 0-4 year old children, 5.4% in 5-9 year old and 6,2% in 10-14 year old youngsters. The differences between both areas were statistically significant (p < 0.005). This study favors serology as a valid indicator for the evaluation of transmission of Chagas disease in rural areas.

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