ANTIFUNGAL ACTIVITY OF Cymbopogon nardus (L.) Rendle (CITRONELLA) AGAINST Microsporum canis FROM ANIMALS AND HOME ENVIRONMENT

Revista do Instituto de Medicina Tropical de São Paulo

Isis Regina Grenier Capoci¹  Michele Milano Da Cunha¹  Patricia De Souza Bonfim-mendonÇa¹  Luciana Dias Ghiraldi-lopes¹  Lilian Cristiane Baeza¹  Erika Seki Kioshima¹  Terezinha Inez Estivalet Svidzinski¹ 

关键词: Citronella;    Microsporum canis;    Dermatophytosis;    Profilaxy;   

DOI  :  10.1590/S0036-46652015000600008

来源: SciELO

【 摘 要 】

Dermatophytosis is a common zoonosis in urban centers. Dogs and cats have played an important role as its disseminators. Environmental decontamination is essential for the prevention of its propagation to humans and animals. However, sanitizers or disinfectants with antifungal activity, currently available, have high toxicity. The present study evaluated the in vitro effects of an extract of citronella (Cymbopogon nardus) on 31 Microsporum canis isolates from animals and home environments. Susceptibility tests were performed based on document M38-A2 (2008) of the Clinical and Laboratory Standards Institute with modifications for natural products. Although susceptibility variation was observed between the fungus tested, the concentrations that inhibited the growth of 50 and 90% of the microorganisms were low (19.5 and 78 µg/mL, respectively). Thus, this citronella extract showed potent fungistatic and fungicide activities against M. canis isolated from animals and home environments. Therefore, it could be an alternative for dermatophytosis prophylaxis in the home environment.

【 授权许可】

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