RENAL HISTOPATHOLOGICAL FINDINGS IN DOGS WITH VISCERAL LEISHMANIASIS

Revista do Instituto de Medicina Tropical de São Paulo

Rosangela Silva Rigo¹  Cristiano Marcelo Espínola Carvalho¹  Michael Robin Honer¹  Gisele Braziliano De Andrade¹  Iandara Shetter Silva¹  Leonardo Rigo¹  Helen Rezende Figueiredo¹  Wanessa Teixeira Gomes Barreto¹ 

关键词: Renal histopathology;    Visceral leishmaniasis;    Dogs;   

DOI  :  10.1590/S0036-46652013000200008

来源: SciELO

【 摘 要 】

Visceral leishmaniasis affects various organs including the kidneys; which can lead to renal failure and death. In order to verify this renal involvement, material was evaluated from 100 dogs naturally infected and with serological diagnosis of canine visceral leishmaniasis (CVL). Inflammatory changes were present in 25.3% of the tubules, in 67.0% of interstitium and in 52.0% of glomeruli. There was no significant difference (p > 0.05) between the presence of glomerulonephritis in symptomatic and oligosymptomatic dogs. The membranous and membranoproliferative glomerulonephritis were the most frequent, both with 18.0% frequency, followed by focal segmental glomerulosclerosis with 14.0%. Changes such as cylindruria, tubular and fibrosis hypertrophy, periglomerular inflammatory infiltrate, and multifocal and diffuse peritubular inflammatory infiltrate were observed. The findings are consistent with those of other authors indicating that renal involvement is common in CVL and the standards of membranous and membranoploriferative glomerulonephritis, as well as the tubulointerstitial involvement, are frequent.

【 授权许可】

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