Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil

Revista do Instituto de Medicina Tropical de São Paulo

William Marciel De Souza²  Alex Martins Machado²  Geonildo Rodrigo Disner¹  Everton Boff¹  Aline Rafaela Da Silva Rodrigues Machado²  Michelly De Padua²  Luiz Tadeu Moraes Figueiredo²  Gustavo Borba De Miranda¹ 

[1] ,Universidade de São Paulo School of Medicine of Ribeirão Preto Virology Research CenterRibeirão Preto SP ,Brazil

关键词: Hantavirus;    Epidemiology;    Brazil;    Argentina;    Santa Catarina;   

DOI  :  10.1590/S0036-46652012000400002

来源: SciELO

【 摘 要 】

Hantavirus cardiopulmonary syndrome (HCPS) is an infectious disease caused by hantaviruses of the family Bunyaviridae, and is transmitted by aerosols of excreta of infected rodents. The aim of the present study was to determine antibody levels to hantavirus in the population that lives at frontier of Brazil and Argentina. Participated of the study 405 individuals living in the municipalities of Bandeirante, Santa Helena, Princesa and Tunapolis, state of Santa Catarina, Brazil. IgG antibodies to hantavirus were analyzed in sera by an ELISA that uses a recombinant N protein of Araraquara hantavirus as antigen. The results were also confirmed by immunofluorescent test. Eight individuals showed antibodies to hantavirus (1.97% positivity), with serum titers ranging from 100 to 800. Six seropositives were males, older than 30 years and farmers. Our results reinforce previous data on hantavirus circulation and human infections in the southern border of Brazil with Argentina.

【 授权许可】

CC BY-NC   
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