On the possibility of autochthonous Chagas disease in Roraima, Amazon region, Brazil, 2000-2001

Revista do Instituto de Medicina Tropical de São Paulo

José Francisco Luitgards-moura²  José Borges-pereira¹  Jane Costa¹  Patrícia Lago Zauza¹  Maria Goreti Rosa-freitas² 

[1] ,Universidade Federal de Roraima Centro de Ciências Biológicas e da Saúde Boa Vista Roraima ,Brasil

关键词: Chagas disease;    Agricultural Settlements;    Amazon;    Roraima;    Brazil;   

DOI  :  10.1590/S0036-46652005000100008

来源: SciELO

【 摘 要 】

Chagas disease has been almost entirely eradicated from the arid zones in Central and Northeastern Brazil where rare or no autochthonous cases have been reported. However, in the last 10 years the disease has increasingly been registered in the Amazon Region. Aiming to investigate the possibility of the occurrence of autochthonous cycle of Chagas disease in Roraima, triatomine collections, vectorial susceptibility studies (this one to be shown elsewhere), parasitological and serological analyses were conducted in three agricultural settlement areas (Rorainópolis, Passarão Project and Ilha Community). Blood-donor candidates were also investigated. This is the first epidemiological survey on Chagas disease conducted in agricultural settlements in Roraima. Triatomine species found were Triatoma maculata, Rhodnius pictipes, Rhodnius robustus and Panstrongylus geniculatus. Trypanosoma cruzi detection analyses included xenodiagnosis, indirect immunofluorescence, indirect hemaglutination, ELISA and kinetoplast PCR amplification. Natural triatomine infection was not found in intestinal contents. Twenty-five adult settlers (1.4% out of 1821, all > 15 year-old, 20 migrants) presented anti-T. cruzi antibodies. Two migrant settlers (from Minas Gerais and Maranhão) tested positive for more than two serological tests, besides either being positive for xenodiagnosis or PCR. Results show that Chagas disease is not endemic in the areas studied. However, all elements of the transmission cycle are present, demanding for an adequate and continuous vigilance.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License