Molecular epidemiology of a nosocomial outbreak due to Enterobacter cloacae and Enterobacter agglomerans in Campinas, São Paulo, Brazil

Revista do Instituto de Medicina Tropical de São Paulo

Célia R. GonÇalves²  Tania M.i. Vaz²  Daniela Leite²  Beatriz Pisani¹  Marise SimÕes¹  Maria Angela M. Prandi¹  Marilu M.m. Rocha¹  Paulo C. Cesar¹  Plinio Trabasso¹  Angela Von Nowakonski¹  Kinue Irino² 

[1] ,Instituto Adolfo LutzSão Paulo SP ,Brasil

关键词: Nosocomial outbreak;    Enterobacter cloacae;    Enterobacter agglomerans;    Serotypes;    Ribotyping;   

DOI  :  10.1590/S0036-46652000000100001

来源: SciELO

【 摘 要 】

A total of 73 isolates (57 Enterobacter cloacae and 16 Enterobacter agglomerans), recovered during an outbreak of bacteremia in the Campinas area, São Paulo, Brazil, were studied. Of these isolates, 61 were from parenteral nutrition solutions, 9 from blood cultures, 2 from a sealed bottle of parenteral nutrition solution, and one was of unknown origin. Of the 57 E. cloacae isolates, 54 were biotype 26, two were biotype 66 and one was non-typable. Of 39 E. cloacae isolates submitted to ribotyping, 87.2% showed the same banding pattern after cleavage with EcoRI and BamHI. No important differences were observed in the antimicrobial susceptibility patterns among E. cloacae isolates exhibiting the same biotype, serotype and ribotype. All E. agglomerans isolates, irrespective of their origin, showed same patterns when cleaved with EcoRI and BamHI. The results of this investigation suggest an intrinsic contamination of parenteral nutrition solutions and incriminate these products as a vehicle of infection in this outbreak.

【 授权许可】

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