Usefulness of the detection of Toxoplasma gondii antigens in AIDS patients

Revista do Instituto de Medicina Tropical de São Paulo

Alberto Fachado¹  Luis Fonte¹  Esteban Alberti¹  Pablo Hadad¹  Lisset Fonseca¹  Rodolfo Machin¹  Carlos Finlay¹ 

关键词: T. gondii;    toxoplasmic encephalitis;    AIDS;   

DOI  :  10.1590/S0036-46651994000600009

来源: SciELO

【 摘 要 】

Toxoplasmic encephalitis (TE) is a mayor cause of central nervous system infection in patients with acquired immunodeficiency syndrome (AIDS). Toxoplasma antibodies were detected in 56 of 79 patients with AIDS (71%), in the present study. Fourteen out of 57 seropositive patients developed TF (25%) and had Toxoplasma gondii antigen detected in their urine. For this, most of them received an effective therapy, with the subsequent disappearance of the symptoms and discontinuity of excretion of the T. gondii antigens. Our results suggest that the monitoring of T. gondii antigen in the urine of AIDS patients may be useful to decide on the proper time for therapy, as well as to avoid the beginning of neurologic signs in these patients.

【 授权许可】

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