Reproductive outcomes in an area adjacent to a petrochemical plant in southern Brazil

Revista de Saúde Pública

Lenice Minussi Oliveira²  Nina Stein¹  Maria Teresa Vieira Sanseverino¹  Vera Maria Ferrão Vargas²  Jandyra Maria Guimarães Fachel¹  Lavínia Schüler² 

[1] ,Universidade Federal do Rio Grande do Sul Departamento de Genética Porto Alegre RS ,Brasil

关键词: Petroleum industry;    Environmental exposure;    Infant;    newborn;    Impacts on health;    Risk Factors;    Infant;    low birth weight;    Case-control studies;    Indústria petroquímica;    Exposição ambiental;    Recém-nascido;    Impactos na saúde.;    Fatores de risco;    Recém-nascido de baixo peso;    Estudos de casos e controles.;   

DOI  :  10.1590/S0034-89102002000100013

来源: SciELO

【 摘 要 】

OBJECTIVE: To evaluate possible adverse reproductive outcomes in an area adjacent to a petrochemical plant in southern Brazil. METHODS: A review of 17,113 birth records of the main hospital of the municipality of Montenegro, southern Brazil, from 1983 to 1998 was carried out. Three groups of cases were selected: (1) newborns with major congenital malformations; (2) newborns with low birth weight (<2,500 g); and (3) stillborns (>500 g). A control was assigned to each case. Controls were the first newborns weighing> or = 2,500 g without malformations and of case-matching sex. Mother's residence during pregnancy was used as an exposure parameter. Statistical analyses were performed using Chi-square test or Fisher test, odds ratio, 0.05 significance level, and 95% confidence interval. RESULTS: For unadjusted analysis, it was found a correlation between low birth weight and geographical proximity of mother's residence to the petrochemical plant (OR = 1.66; 95% CI = 1.01--2.72) or residence on the way of preferential wind direction (OR = 1.62; 95% CI = 1.03--2.56). When other covariates were added in the conditional logistic regression (maternal smoking habits, chronic disease and age), there was no association. CONCLUSIONS: Despite final results were negative, low birth weight could be a good parameter of environmental contamination and should be closely monitored in the studied area.

【 授权许可】

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