Combination of pharmacotherapy and lidocaine analgesic block of the peripheral trigeminal branches for trigeminal neuralgia: a pilot study

Arquivos de Neuro-Psiquiatria

Fabrizio Di Stani¹  Christine Ojango¹  Demo Dugoni¹  Luigi Di Lorenzo¹  Salvatore Masala¹  Roberto Delfini¹  Gianluca Bruti¹  Giovanni Simonetti¹  Elcio Juliato Piovesan¹  Andrea Gennaro Ruggeri¹ 

关键词: analgesic block;    classical trigeminal neuralgia;    lidocaine;    treatment;    bloqueio analgésico;    lidocaína;    neuralgia trigeminal clássica;    tratamento;   

DOI  :  10.1590/0004-282X20150077

来源: SciELO

【 摘 要 】

Classical trigeminal neuralgia (CTN) is treated predominantly by pharmacotherapy but side effects and unsuccessful occurs. The current study was carried out to evaluate the therapeutic effect of combination of pharmacotherapy and lidocaine block. Thirteen patients with CTN managed with pharmacotherapy were recruited and assigned either to no additional treatment (Group I) or to additional analgesic block (Group II). The primary endpoint was the reduction in the frequency of pain episodes in a month assessed at 30 and 90 days. Comparisons of measurements of pain, general health and depression scales were secondary endpoints. The results from the follow-up visits at 30 and 90 days showed the Group II to have larger reduction in the frequency of pain and exhibited a bigger improvement in the scores of the pain, general health and depression scales. The results from this preliminary study suggest a clinical benefit of the combination of pharmacotherapy and lidocaine block.

【 授权许可】

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