Neurotrophic factors in tension-type headache

Arquivos de Neuro-Psiquiatria

Renan B. Domingues¹  Halina Duarte¹  Natália P. Rocha¹  Antonio L. Teixeira¹ 

关键词: tension-type headache;    neurotrophic factors;    depression;    anxiety;    cefaleia do tipo tensional;    fatores neurotróficos;    depressão;    ansiedade;   

DOI  :  10.1590/0004-282X20150000

来源: SciELO

【 摘 要 】

Neurotrophic factors (NF) are involved in pain regulation and a few studies have suggested that they may play a pathophysiological role in primary headaches. The aim of this study was to investigate NF levels in patients with tension type headache (TTH). We carried out a cross sectional study including 48 TTH patients and 48 age and gender matched controls. Beck Depression and Anxiety Inventories, and Headache Impact Test were recorded. Serum levels of NF were determined by ELISA. There were not significant differences between NF levels between TTH patients and controls. Patients with chronic and episodic TTH had not significant differences in NF levels. The presence of headache at the time of evaluation did not significantly alter the levels of NF. Depression and anxiety scores as well as headache impact did not correlate with NF levels. Our study suggest that the serum levels of NF are not altered in TTH.

【 授权许可】

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