Arquivos de Neuro-Psiquiatria | |
A Case-Control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD) | |
Francisco De Assis Aquino Gondim1  Gisele Ramos De Oliveira1  Benedito Cadorno V. Teles1  Marcellus H.l.p. Souza1  Lucia L.b.c. Braga1  Erick L. Messias1  | |
关键词: Chron's disease; inflammatory bowel disease; peripheral neuropathy; small fiber neuropathy; ulcerative colitis; doença de Crohn; doença inflamatória intestinal; neuropatia periférica; neuropatia de fibras grossas; colite ulcerativa; | |
DOI : 10.1590/0004-282X20140223 | |
来源: SciELO | |
【 摘 要 】
Neurological diseases are common in inflammatory bowel disease (IBD) patients, but their exact prevalence is unknown. Method We prospectively evaluated the presence of neurological disorders in 121 patients with IBD [51 with Crohn's disease (CD) and 70 with ulcerative colitis (UC)] and 50 controls (gastritis and dyspepsia) over 3 years. Results Our standard neurological evaluation (that included electrodiagnostic testing) revealed that CD patients were 7.4 times more likely to develop large-fiber neuropathy than controls (p = 0.045), 7.1 times more likely to develop any type of neuromuscular condition (p = 0.001) and 5.1 times more likely to develop autonomic complaints (p = 0.027). UC patients were 5 times more likely to develop large-fiber neuropathy (p = 0.027) and 3.1 times more likely to develop any type of neuromuscular condition (p = 0.015). Conclusion In summary, this is the first study to prospectively establish that both CD and UC patients are more prone to neuromuscular diseases than patients with gastritis and dyspepsia.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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