Current perspectives in stem cell therapy for spinal cord repair in humans: a review of work from the past 10 years

Arquivos de Neuro-Psiquiatria

Eric Domingos Mariano¹  Chary Marquez Batista¹  Breno José Alencar Pires Barbosa¹  Suely Kazue Nagahashi Marie¹  Manoel Jacobsen Teixeira¹  Matthias Morgalla¹  Marcos Tatagiba¹  Jun Li¹  Guilherme Lepski¹ 

关键词: spinal cord injury;    amyotrophic lateral sclerosis;    stem cells;    stem cell therapy;    lesão medular;    esclerose lateral amiotrófica;    células tronco;    terapia com células tronco;   

DOI  :  10.1590/0004-282X20140051

来源: SciELO

【 摘 要 】

Spinal cord injury (SCI) and amyotrophic laterals sclerosis (ALS) are devastating neurological conditions that affect individuals worldwide, significantly reducing quality of life, both for patients and their relatives.Objective : The present review aims to summarize the multiple restorative approaches being developed for spinal cord repair, the use of different stem cell types and the current knowledge regarding stem cell therapy. Method : Review of the literature from the past 10 years of human studies using stem cell transplantation as the main therapy, with or without adjuvant therapies. Conclusion : The current review offers an overview of the state of the art regarding spinal cord restoration, and serves as a starting point for future studies.

【 授权许可】

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