Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program

Arquivos de Neuro-Psiquiatria

Leonardo Halley Carvalho Pimentel¹  Francisco José Alencar¹  Leonardo Raphael Santos Rodrigues¹  Francisca Cléa Florenço De Sousa¹  João Batista Mendes Teles¹ 

关键词: botulinum toxin type A;    stroke;    spasticity;    toxina botulínica tipo A;    acidente vascular cerebral;    espasticidade;   

DOI  :  10.1590/0004-282X20130189

来源: SciELO

【 摘 要 】

The objective of this study was to evaluate the effects of botulinum toxin type A (BTX-A) on spastic foot in stroke patients in a rehabilitation program.Method: Hemiparetic stroke patients (n=21) enrolled in a rehabilitation program were divided into two groups. The first group (n=11) received a total of 300UI BTX-A, and the second group (n=10) received 100 UI BTX-A. All patients were assessed at baseline and 2, 4, 8 and 12 weeks after injection for Modified Ashworth Score, time walking 10 meters, and the Functional Independence Measure (mFIM) motor score. Results: The higher-dose group exhibited a significant improvement in spasticity, and both groups showed an improvement in time walking 10 meters and mFIM, with no significant differences between them. Conclusions: Our findings suggest that gains in gait velocity and functional independence were not correlated to BTX-A dose.

【 授权许可】

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