Syncope in patients with drug-resistant epilepsy without apparent cardiovascular disease

Arquivos de Neuro-Psiquiatria

Soniza Vieira Alves-leon¹  Moises Pereira Pinto¹  Maria Emilia Cosenza Andraus¹  Valeria Coelho Santa Rita Pereira¹  Isabella D'andrea Meira¹  Raquel De Carvalho Oliveira¹  Shaylla Villas Boas¹  Claudia Cecilia Da Silva Rego¹  Jorge Paes Barreto Marcondes De Souza¹  Roberto Coury Pedrosa¹ 

关键词: drug-resistant epilepsy;    epilepsy;    inclination test;    syncope;    pseudoseizures;    epilepsia farmaco-resistente;    epilepsia;    teste de inclinacao;    pseudocrises;   

DOI  :  10.1590/0004-282X20130179

来源: SciELO

【 摘 要 】

Epilepsy and syncope are clinical conditions with high prevalence rates in the general population, and the differential diagnosis between them is difficult.Objective To assess the frequency of syncope in patients diagnosed with drug-resistant epilepsy (DRE) without appa­rent heart disease, to investigate the relationship between clinical and electroencephalographic (EEG) changes, and to verify the role of the inclination test (IT). Method An open, prospective study from 2004 to 2006, including 35 consecutive patients from the Epilepsy Program of Hospital Universitário Clementino Fraga Filho who were diagnosed with DRE without apparent heart disease. Results The frequency of syncope was 25.7% (n=9), with a significant prevalence in women. Vasovagal syncope (VVS) was the most frequent diagnosis. Conclusion We found a significant association between syncope and the presence of autonomic symptoms (p=0.005). The IT plays an important role in the differential diagnosis of patients with DRE presenting with autonomic symptoms, regardless of EEG results and brain magnetic resonance imaging (MRI) abnormalities.

【 授权许可】

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