Multiple sclerosis starting before the age of 18 years: the Brazilian experience

Arquivos de Neuro-Psiquiatria

Yara Dadalti Fragoso¹  Maria Lucia Brito Ferreira¹  Nivea De Macedo Oliveira Morales¹  Walter Oleschko Arruda¹  Joseph Bruno Bidin Brooks¹  Denise Sisterolli Diniz Carneiro¹  Margarete De Jesus Carvalho¹  Elizabeth Regina Comini-frota¹  Eber Castro Correa¹  Carlos Augusto De Albuquerque Damasceno¹  Renan Barros Domingues¹  Alessandro Finkelsztejn¹  Paulo Diniz Da Gama¹  Sidney Gomes¹  Marcus Vinicius Magno Goncalves¹  Anderson Kuntz Grzesiuk¹  Jussara Mathias Netto Khouri¹  Damacio Ramon Kaimen-maciel¹  Maria Fernanda Mendes¹  Rogerio De Rizo Morales¹  Sonia Beatriz Felix Ribeiro¹  Taysa Alexandrino Gonsalves Jube Ribeiro¹  Livia Brito Bezerra De Albuquerque¹  Andrea Anacleto¹  Juliana Finkelsztejn¹  Rodrigo Assad Diniz Da Gama¹  Josiane Lopes¹  Celso Luis Silva Oliveira¹  Francisco Tomaz Meneses Oliveira¹  Leopoldo Antonio Pires¹  Patricia Correia De Oliveira Saldanha¹  Adelia Henriques Souza¹  Alex Eduardo Da Silva¹ 

关键词: multiple sclerosis;    children;    adolescents;    pediatrics;    esclerose multipla;    criancas;    adolescentes;    pediatria;   

DOI  :  10.1590/0004-282X20130122

来源: SciELO

【 摘 要 】

Multiple sclerosis (MS) starting in childhood and adolescence poses a challenge for diagnosis and management of the disease. The aim of the present study was to assess the characteristics of early onset MS in Brazilian patients.Methods Retrospective data collection from specialized MS units. Results From 20 MS units in 11 Brazilian states, 117 cases of MS starting before the age of 18 years were collected. These patients had an average of 10 years of disease duration, still typically with low disability and one relapse every 2.5 years. The mean age for disease onset was 13.7 years. Conclusion The present study introduces a large series of Brazilian cases of pediatric MS. Although some patients presented a very severe form of MS, on the whole the group of patients with MS starting in childhood or adolescence presented a relatively mild form of this disease in Brazil.

【 授权许可】

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