Arquivos de Neuro-Psiquiatria | |
White matter hyperintensities, executive function and global cognitive performance in vascular mild cognitive impairment | |
Felipe Kenji Sudo1  Carlos Eduardo Oliveira Alves1  Gilberto Sousa Alves1  Letice Ericeira-valente1  Chan Tiel1  Denise Madeira Moreira1  Jerson Laks1  Eliasz Engelhardt1  | |
关键词: mild cognitive impairment; dementia; vascular; executive function; neuropsychology; neuroimaging; cerebrovascular disorders; comprometimento cognitivo leve; demência vascular; função executiva; neuropsicologia; neuroimagem; transtornos cerebrovasculares; | |
DOI : 10.1590/0004-282X20130057 | |
来源: SciELO | |
【 摘 要 】
Vascular mild cognitive impairment (VaMCI) represents an early symptomatic stage of vascular cognitive impairment and might be associated to fronto-executive dysfunction.MethodsTwenty-six individuals (age: 73.11±7.90 years; 65.4% female; schooling: 9.84±3.61 years) were selected through neuropsychological assessment and neuroimaging. Clinical and neuroimaging data of VaMCI individuals (n=15) were compared to normal controls (NC, n=11) and correlated with Fazekas scale.ResultsVaMCI performed significantly worse than NC in Trail-Making Test (TMT) B, errors in TMT B, difference TMT B-A and Cambridge Cognitive Examination (CAMCOG) final scores. Correlations were found among scores in modified Fazekas scale and performances in TMT B (time to complete and errors), difference TMT B-A and CAMCOG total score.ConclusionExtension of white matter hyperintensities might be correlated to poorer global cognition and impairments in a set of fronto-executive functions, such as cognitive speed, set shifting and inhibitory control in VaMCI.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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