Neurological disorders associated with glutamic acid decarboxylase antibodies: a Brazilian series

Arquivos de Neuro-Psiquiatria

Maurício Fernandes²  Renato P. Munhoz¹  Paulo Eduardo Mestrinelli Carrilho¹  Walter O. Arruda²  Paulo J. Lorenzoni²  Rosana H. Scola²  Lineu César Werneck²  Hélio A. G. Teive² 

[1] ,Universidade Federal do Paraná Hospital de Clínicas Internal Medicine DepartmentCuritiba PR ,Brazil

关键词: glutamic acid decarboxylase antibodies;    anti-GAD;    neurological disorders;    stiff-person syndrome;    cerebellar ataxia;    anticorpos anti-descaboxilase do ácido glutâmico;    anti-GAD;    distúrbios neurológicos;    rigidez muscular espasmódica;    ataxia cerebelar;   

DOI  :  10.1590/S0004-282X2012000900002

来源: SciELO

【 摘 要 】

Neurological disorders associated with glutamic acid decarboxylase (GAD) antibodies are rare pleomorphic diseases of uncertain cause, of which stiff-person syndrome (SPS) is the best-known. Here, we described nine consecutive cases of neurological disorders associated with anti-GAD, including nine patients with SPS and three cases with cerebellar ataxia. Additionally, four had hypothyroidism, three epilepsy, two diabetes mellitus and two axial myoclonus.

【 授权许可】

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