Bridge-therapy with enoxaparin in the preoperative period of endarterectomy

Arquivos de Neuro-Psiquiatria

Jair Leopoldo Raso¹  Rogério Zenóbio Darwich¹  Francisco De Lucca Jr¹  Romeu Valle Santana¹  Marco Túlio Tanure¹  Gustavo Agra Cariri¹  Leopoldo Mandic Ferreira Furtado¹ 

[1] ,Biocor Instituto Instituto Mineiro de Neurocirurgia Belo Horizonte MG ,Brazil

关键词: antiplatelet drugs;    cervical clot;    endarterectomy;    enoxaparin;    stroke;    antiagregante plaquetário;    AVC;    endarterectomia;    enoxaparina;    hematoma cervical;   

DOI  :  10.1590/S0004-282X2010000500019

来源: SciELO

【 摘 要 】

Cervical clot is one of the complications of endarterectomy. This risk may be higher in patients using aspirin or clopidogrel. On the other hand, stroke may occur if the medication is interrupted before surgery. We carried out a prospective study of 124 endarterectomies in 119 patients in which aspirin or clopidogrel was stopped and a bridge-therapy with enoxaparin was administered preoperatively. There was no case of stroke during the period of the bridge-therapy. One patient developed cervical clot (0.8%) in the fifth postoperative day. Mortality rate in this series was 0.8%. There was no complication directly related to the use of enoxaparin. Bridge-therapy with low molecular weight heparin is a safe strategy for patients elected for endarterectomy

【 授权许可】

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