Arquivos de Neuro-Psiquiatria | |
Patent foramen ovale in trigeminal autonomic cephalalgias and hemicrania continua: a non-specific pathophysiological occurrence? | |
Vanise Amaral1  Gabriel R. De Freitas2  Bruno C.b Rodrigues2  Daniel De H Christoph1  Carlos A. De Pinho2  Cristiana De Faria P Góes1  Maurice B Vincent1  | |
[1] ,Instituto D'Or de Pesquisa e Ensino Hospital Quinta D'Or Rio de Janeiro RJ ,Brazil | |
关键词: patent foramen ovale; right-to-left shunt; cluster headache; paroxysmal hemicrania; migraine; SUNCT; hemicrania continua; foramen oval patente; shunt direito-esquerdo; cefaléia em salvas; hemicrania paroxística; enxaqueca; SUNCT; hemicrania continua; | |
DOI : 10.1590/S0004-282X2010000400028 | |
来源: SciELO | |
【 摘 要 】
Patent foramen ovale (PFO), a relatively common abnormality in adults, has been associated with migraine. Few studies also linked PFO with cluster headache (CH). To verify whether right-to-left shunt (RLS) is related to headaches other than migraine and CH, we used transcranial Doppler following microbubbles injection to detect shunts in 24 CH, 7 paroxysmal hemicrania (PH), one SUNCT, two hemicrania continua (HC) patients; and 34 matched controls. RLS was significantly more frequent in CH than in controls (54% vs. 25%, p=0.03), particularly above the age of 50. In the HC+PH+SUNCT group, RLS was found in 6 patients and in 2 controls (p=0.08). Smoking as well as the Epworth Sleepiness Scale correlated significantly with CH, smoking being more frequent in patients with RLS. PFO may be non-specifically related to trigeminal autonomic cephalalgias and HC. The headache phenotype in PFO patients probably depends on individual susceptibility to circulating trigger factors.
【 授权许可】
CC BY
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