Attention deficit and hyperactivity disorder in people with epilepsy: diagnosis and implications to the treatment

Arquivos de Neuro-Psiquiatria

Julio A.s. Koneski²  Erasmo B. Casella¹ 

[1] ,Joinville Region University São Paulo University Department of Neurology of São Paulo Medical SchoolSão Paulo SP ,Brazil

关键词: ADHD;    epilepsy;    methylphenidate;    comorbidities;    seizures;    antiepileptic drugs;    TDAH;    epilepsia;    metilfenidato;    comorbidades;    convulsão;    drogas antiepilépticas;   

DOI  :  10.1590/S0004-282X2010000100023

来源: SciELO

【 摘 要 】

The association between attention deficit and hyperactivity disorder (ADHD) and epilepsy can cause significant impact on the social life of affected individuals and their families. Clinical studies suggest that 30-40% of people with epilepsy also have ADHD. There are no studies which demonstrate that short or long-term treatment with methylphenidate increases the risk of seizures. Some studies attempt to relate drug interactions between methylphenidate and antiepileptic drugs, but adverse effects of methylphenidate have not been shown clearly. This review presents some neurobiological and physiopathogenic aspects, common to ADHD and epilepsy, from recent research studies, related to pharmacology, neuroimaging and electroencephalography. Possible risk of occurrence of seizures associated with the use of methylphenidate are also discussed.

【 授权许可】

CC BY   
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