Regional cooling for reducing brain temperature and intracranial pressure

Arquivos de Neuro-Psiquiatria

Luis Vicente Forte¹  Cássio Morano Peluso¹  Mirto Nelso Prandini¹  Roberto Godoy¹  Salomon Soriano Ordinola Rojas¹ 

[1] ,Hospital São Joaquim, Real e Benemérita Sociedade Portuguesa de Beneficência de São Paulo Hospital Meridional Neurosurgical Intensive Care UnitSão Paulo SP ,Brazil

关键词: intracranial hypertension;    intracranial pressure;    cerebral hypothermia;    brain edema;    brain injuries;    hipertensão intracraniana;    pressão intracraniana;    hipotermia induzida;    edema encefálico;    traumatismos encefálicos;   

DOI  :  10.1590/S0004-282X2009000300019

来源: SciELO

【 摘 要 】

OBJECTIVE: To evaluate the effectiveness of regional cooling for reducing brain temperature (BrTe) and intracranial pressure (ICP) in patients where conventional clinical treatment has failed. METHOD: Regional cooling was carried out using ice bags covering the area of the craniectomy (regional method) in 23 patients. The BrTe and ICP were determined using a fiber optic sensor. Thirteen patients (56.52%) were female. The ages ranged from 16 to 83 years (mean of 48.9). The mean APACHE II score was 25 points (11-35). The patients were submitted, on mean, to 61.7 hours (20-96) of regional cooling. RESULTS: There was a significant reduction in mean BrTe (p<0.0001-from 37.1ºC to 35.2ºC) and mean ICP (p=0.0001-from 28 mmHg to 13 mmHg). CONCLUSION: Our results suggest that mild brain hypothermia induced by regional cooling was effective in the control of ICP in patients who had previously undergone decompressive craniectomy.

【 授权许可】

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