Retrocollis, anterocollis or head tremor may predict the spreading of dystonic movements in primary cervical dystonia

Arquivos de Neuro-Psiquiatria

Clecio Godeiro-junior¹  Andre Carvalho Felício¹  Patrícia Maria De Carvalho Aguiar¹  Vanderci Borges¹  Sonia Maria Azevedo Silva¹  Henrique Ballalai Ferraz¹ 

[1] ,Federal University of São Paulo Department of Neurology and Neurosurgery Movement Disorders UnitSão Paulo SP ,Brazil

关键词: cervical dystonia;    progression;    retrocollis;    anterocollis;    head tremor;    distonia cervical;    progressão;    retrocolis;    anterocolis;    tremor cefálico;   

DOI  :  10.1590/S0004-282X2009000300006

来源: SciELO

【 摘 要 】

BACKGROUND AND PURPOSE: Few studies have attempted to develop clinical predictors for cervical dystonia (CD) aiming at progression of the dystonic movement. METHOD: We retrospectively evaluated 73 patients with primary CD who underwent treatment with Botulinum toxin type-A (BTX-A). The patients were assembled in two groups according to the spread of dystonia during follow-up: spreading and non-spreading CD. We performed a binary logistic regression model using spreading of cervical dystonia as dependent variable aiming to find covariates which increase the risk of spreading. RESULTS: Our logistic regression model found the following covariates and their respective risk ratios: time of disease >18.5 months=2.4, retrocollis=1.9, anterocollis=1.8, head tremor=1.6. CONCLUSION: Time of disease >18.5 months, retrocollis, anterocollis and head tremor may predict spreading of dystonic movement to other regions of the body in CD patients.

【 授权许可】

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