Multiple intracranial meningiomas: diagnosis, biological behavior and treatment

Arquivos de Neuro-Psiquiatria

José Carlos Lynch¹  Leandro Alcy Sales Ferreira¹  Leonardo Welling¹  Renata Cardoso Schulz¹ 

[1] ,Hospital dos Servidores do Estado Serviço de Neurocirurgia Rio de Janeiro RJ ,Brazil

关键词: brain tumors;    meningiomas;    multiple intracranial meningiomas;    microneurological surgery;    tumor cerebral;    meningiomas;    meningiomas intracranianos múltiplos;    microneurocirurgia;   

DOI  :  10.1590/S0004-282X2008000500018

来源: SciELO

【 摘 要 】

Multiple intracranial meningiomas (MIM) are a rare pathology when not associated with neurofibromatosis. The prevalence rate of those tumors varied from 2.3 to 8.9% of all intracranial meningiomas. OBJECTIVE: To present, analyze and discuss the cases of seven patients diagnosed with multiple intracranial meningiomas, describing their clinical and histological characteristics, as well as their biological behavior. METHOD: The patients records, surgical descriptions, imaging studies and the histopathological exams were retrospectively reviewed. This is the largest series of MIM publisted in Brazil. RESULTS: This sample consists of five women and two men. The age varied from 42 to 84 (average 53.8). Twenty-two meningiomas were identified and varied from 1.5 to 192 cm³, with an 62.8 cm³ average volume. The number of procedures varied from 1 to 5 per patient. No surgical death occurred in this series. CONCLUSION: Despite the multiplicity of tumors, number of recurrences, the new tumors, repeated operations and re-operations, radiotherapy and a number of postoperative complications, the patients experienced a long survival in conjunction with a fairly good quality of life.

【 授权许可】

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