Beneficial effects of botulinum toxin type A in trigeminal neuralgia

Arquivos de Neuro-Psiquiatria

Carlos Zúñiga¹  Sergio Díaz¹  Fabián Piedimonte¹  Federico Micheli¹ 

[1] ,Hospital de Clínicas José de San Martín Parkinson's Disease and Movement Disorders Unit Buenos Aires,Argentina

关键词: trigeminal neuralgia;    botulinum toxin;    facial pain;    neuralgia trigeminal;    toxina botulínica;    dolor facial;   

DOI  :  10.1590/S0004-282X2008000400012

来源: SciELO

【 摘 要 】

Botulinum toxin has been thoroughly studied as a potential tool in the treatment of several pain syndromes. Therefore, we assessed the clinical effects of botulinum toxin type A injections in 12 patients with otherwise unresponsive idiopathic trigeminal neuralgia. Patients were infiltrated with 20-50 units of botulinum toxin in trigger zones. Those who presented with mandibular involvement were also infiltrated in the masseter muscle. The patients were assessed on a weekly basis using the Visual Analogic Scale for pain. Ten of our patients reported a significant benefit from botulinum toxin injections, with reduction or even disappearance of pain, and remained pain free for as long as 60 days. Our findings suggest that botulinum toxin may represent a useful therapeutic tool in the management of patients with this entity.

【 授权许可】

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