Amyotrophic lateral sclerosis: combined nutritional, respiratory and functional assessment

Arquivos de Neuro-Psiquiatria

Luciano Bruno De Carvalho Silva²  Lucia Figueiredo Mourão¹  Ariovaldo Armando Silva¹  Núbia Maria Freire Vieira Lima¹  Sara Regina Almeida¹  Marcondes C. Franca Jr¹  Anamarli Nucci¹  Jaime Amaya-farfán¹ 

[1] ,University of Campinas School of Food Engineering Center for Food Security StudiesCampinas SP ,Brazil

关键词: amyotrophic lateral sclerosis;    nutritional support;    respiratory tests;    ALSFRS scale;    esclerose lateral amiotrófica;    suporte nutricional;    testes respiratórios;    escala ALSFRS-R;   

DOI  :  10.1590/S0004-282X2008000300014

来源: SciELO

【 摘 要 】

OBJECTIVE: To establish correlations between nutritional, functional and respiratory indices of patients with amyotrophic lateral sclerosis (ALS). METHOD: Twenty patients (13 appendicular - GA and 7 bulbar - GB) were included in the multidisciplinary study at the Neurological Clinic Ambulatory of the University of Campinas Hospital. RESULTS: Among the GA type significant correlation was observed between maximal inspiratory (MIP) and expiratory (MEP) pressure (r= -0.76), MEP and pulse oxymetry (r=0.58), MIP and percent weight loss (%WL; r=0.59), and between MIP, total and subscale respiratory scores (ALSFRS-R) with %WL. With regard to the GB, correlation was found between MEP and body mass index (BMI) (r=0.97). In both GA and GB correlations were noticed between the BMI and the variables mass (kg), fat (%), arm and wrist circumference (cm), and tricipital, subscapular and supra-iliac skinfolds (mm), as well as the arm muscle circumference (cm) and fatty arm muscular area (mm²). CONCLUSION: It is suggested that the application of simple anthropometric measurements could be useful in routine monitoring of patients with ALS.

【 授权许可】

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