Stroke in patients with sickle cell disease: clinical and neurological aspects

Arquivos de Neuro-Psiquiatria

Carolina Camargo De Oliveira¹  Sylvia Maria Ciasca¹  M. Valeriana L. Moura-ribeiro¹ 

[1] ,Universidade Estadual da Campinas Faculdade de Ciências Médicas Departamento de NeurologiaCampinas SP ,Brasil

关键词: stroke;    sickle cell anemia;    neurological manifestations;    acidente cerebrovascular;    anemia falciforme;    manifestações neurológicas;   

DOI  :  10.1590/S0004-282X2008000100008

来源: SciELO

【 摘 要 】

The aim of this study was to characterize a group of patients (n=8) with sickle cell disease (SCD) and ischemic stroke concerning the clinical, neurological, imaging and progressive aspects. Data were collected from records and completed with an interview of patients and their parents. In this study there were 8 patients with ages ranging from 10 to 23 years old; SCD diagnosis was given between one and two years of age with clinical features of fatigue and anemia. The stroke was ischemic in all individuals and the first cerebrovascular event occurred before 6 years of age; 3 patients had recurrence of stroke despite prophylactic blood transfusion therapy and both cerebral hemispheres were affected in 4 patients. Clinical and neurological current features observed were: acute pain crises, sialorrhea, mouth breathing, motor, and neuropsychological impairments resulting from cortical-subcortical structure lesions.

【 授权许可】

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