Tuberculosis: an uncommon cause of cerebral venous thrombosis?

Arquivos de Neuro-Psiquiatria

José Antonio Fiorot Júnior²  André Carvalho Felício²  Márcia Mauimi Fukujima²  Celso Arraes Rodrigues¹  Vânia Maria Morelli¹  Dayse Maria Lourenço¹  Gilmar Fernandes Do Prado² 

[1] ,Universidade Federal de São Paulo Division of Neurology São Paulo SP ,Brazil

关键词: cerebral venous thrombosis;    tuberculosis;    prothrombin gene mutation;    trombose venosa cerebral;    tuberculose;    mutação do gene da protrombina;   

DOI  :  10.1590/S0004-282X2005000500025

来源: SciELO

【 摘 要 】

Several infectious etiologies are related to cerebral venous thrombosis (CVT), but a review of literature showed only few cases related to tuberculosis (TB), and only one with neurological manifestations.We report an unusual case of CVT related to TB and mutation in prothrombin gene. A 38-man black presented abrupt right hemiparestesis, and hemiparesis. Investigations revealed CVT. Cerebral spinal fluid (CSF) examination evidenced a infection by Mycobacterium. He was heterozygous for G20210A prothrombin mutation. Probably, hypercoagulability mechanisms of TB, added to mutation of prothrombim gene increase the risk of CVT.

【 授权许可】

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